What is Palmitoyl Pentapeptide-4?

Palmitoyl Pentapeptide-4 is a synthetic peptide, a small chain of amino acids, that is designed to mimic a natural skin protein fragment. It is commonly used in anti-aging skincare products.

How does Palmitoyl Pentapeptide-4 work in skincare?

It is thought to signal the skin to produce more collagen, a key protein for skin structure and elasticity. This action can help reduce the visible signs of aging, such as fine lines and wrinkles.

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Palmitoyl Pentapeptide-4

Palmitoyl Pentapeptide-4 is a synthetic peptide that mimics a fragment of collagen type I. It is believed to stimulate collagen production in the skin. This can help improve the appearance of fine lines and wrinkles, contributing to a smoother skin texture.

NonePeptideVeganEvidence: Medium

BenefitGood 2.8 / 4

Anti aging i2.8 / 4

Whether it can help visible signs of aging — fine lines, wrinkles, loss of firmness, or photoaging.

Texture i2.5 / 4

Whether it can improve smoothness and surface texture — roughness, flaking, clogged pores, or unevenness. Exfoliating acids, retinoids, and smoothing moisturizers may score here.

RiskVery low 0 / 4

Rated by SpottyLabs' ingredient methodology, independent of brands.

What it helps with

Reduces appearance of wrinkles
Improves skin firmness
Supports collagen production

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Products with Palmitoyl Pentapeptide-4

The Ordinary

Aloe 2% + NAG 2% Solution

4.2/ 59/5/4

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Frequently asked questions

What is Palmitoyl Pentapeptide-4?: Palmitoyl Pentapeptide-4 is a synthetic peptide, a small chain of amino acids, that is designed to mimic a natural skin protein fragment. It is commonly used in anti-aging skincare products.
How does Palmitoyl Pentapeptide-4 work in skincare?: It is thought to signal the skin to produce more collagen, a key protein for skin structure and elasticity. This action can help reduce the visible signs of aging, such as fine lines and wrinkles.