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Zinc Pyrithione

Zinc pyrithione is an antifungal and antibacterial agent widely used in anti-dandruff shampoos and some topical skin treatments. It works by inhibiting the growth of yeast and bacteria that contribute to scalp conditions like dandruff and seborrheic dermatitis. It is not typically used in leave-on facial skincare products.

Antifungal agentVegan
BenefitStrong 3.5 / 4
Soothing i1 / 4

Whether it can calm the skin — linked to less redness, irritation, discomfort, or visible reactivity.

Acne i1 / 4

Whether it can help acne-prone skin — reducing clogged pores, excess oil, acne-causing bacteria, inflammation, or breakouts.

RiskHigh 2.5 / 4
Irritation i2 / 4

Risk of short-term irritation — stinging, burning, dryness, redness, or discomfort. Common for strong actives, acids, retinoids, fragrances, and harsh surfactants.

Systemic exposure i1 / 4

Whether it has meaningful potential to be absorbed into the body at levels that may matter biologically. Most cosmetic ingredients score low unless there is known concern or high exposure.

Sensitization i1 / 4

Risk of allergic contact dermatitis or immune-based reactions. Fragrance allergens, preservatives, botanicals, and some dyes may score here.

Rated by SpottyLabs' ingredient methodology, independent of brands.

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Products with Zinc Pyrithione

Classic Clean Anti-Dandruff Shampoo & Conditioner 2-in-1
Head & Shoulders
Classic Clean Anti-Dandruff Shampoo & Conditioner 2-in-1
4.2/ 52/8/6

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Frequently asked questions

How does zinc pyrithione treat dandruff?
Zinc pyrithione treats dandruff by slowing the growth of Malassezia globosa, a yeast-like fungus that is a primary cause of dandruff and seborrheic dermatitis.
Is zinc pyrithione safe for colored hair?
Zinc pyrithione is generally considered safe for colored hair, but some individuals may experience slight color dulling. It is best to follow product instructions.