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Thioctic Acid

Thioctic acid, also known as alpha-lipoic acid (ALA), is a potent antioxidant naturally found in the body. It is unique because it is both water- and fat-soluble, allowing it to work in various parts of the cell. In skincare, it helps to neutralize free radicals, which can contribute to premature skin aging and damage.

AntioxidantVegan
BenefitGood 2.8 / 4
Anti aging i2.5 / 4

Whether it can help visible signs of aging — fine lines, wrinkles, loss of firmness, or photoaging.

Pigmentation i1 / 4

Whether it can help uneven tone, dark spots, melasma-like discoloration, or post-inflammatory hyperpigmentation — including brightening and tyrosinase-inhibiting ingredients.

Texture i1 / 4

Whether it can improve smoothness and surface texture — roughness, flaking, clogged pores, or unevenness. Exfoliating acids, retinoids, and smoothing moisturizers may score here.

RiskModerate 1.5 / 4
Irritation i1.5 / 4

Risk of short-term irritation — stinging, burning, dryness, redness, or discomfort. Common for strong actives, acids, retinoids, fragrances, and harsh surfactants.

Sensitization i1 / 4

Risk of allergic contact dermatitis or immune-based reactions. Fragrance allergens, preservatives, botanicals, and some dyes may score here.

Rated by SpottyLabs' ingredient methodology, independent of brands.

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Frequently asked questions

What makes thioctic acid a unique antioxidant?
Thioctic acid is unique because it is both water-soluble and fat-soluble, allowing it to function as an antioxidant in both aqueous and lipid environments within the skin cells.
Can thioctic acid be used with other active ingredients?
Yes, thioctic acid can be used with other active ingredients, particularly other antioxidants like Vitamin C, as it can help to regenerate them and boost their efficacy.