Tetramethyl Acetyloctahydronaphthalenes
Also known as: Tetramethyl Acetyloctahydronaphthalene
Tetramethyl acetyloctahydronaphthalenes, commonly known as Iso E Super or OTNE, is a synthetic fragrance ingredient that provides a warm, woody, and amber-like scent. It is used strictly for its aromatic qualities and offers no direct therapeutic or restorative skin benefits. Although safe for the general population at regulated concentrations, it is an established contact allergen capable of inducing sensitization or skin irritation in susceptible individuals.
Synthetic fragranceVegan
RiskModerate 1.5 / 4
Sensitization i1.5 / 4
Risk of allergic contact dermatitis or immune-based reactions. Fragrance allergens, preservatives, botanicals, and some dyes may score here.
Systemic exposure i0.5 / 4
Whether it has meaningful potential to be absorbed into the body at levels that may matter biologically. Most cosmetic ingredients score low unless there is known concern or high exposure.
Rated by SpottyLabs' ingredient methodology, independent of brands.
Things to watch
- Potential skin sensitization
- Allergic contact dermatitis in sensitive skin
See how this matches your skin
Find out exactly what you put onto your skin. Scan any product before you buy. Free and independent — no brand is paying us. Available on Android and iOS.
Products with Tetramethyl Acetyloctahydronaphthalenes
Browse all products →
Frequently asked questions
- What is tetramethyl acetyloctahydronaphthalenes?
- It is a widely used synthetic aroma chemical, often marketed as Iso E Super, that imparts a subtle woody and cedar-like note to cosmetic formulations.
- Can this ingredient irritate sensitive skin?
- Yes, it is a recognized fragrance allergen that may cause allergic contact dermatitis or irritation in people with fragrance sensitivities.
