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Squalene

Squalene is a natural lipid found in human sebum and various plant and animal sources. It acts as an emollient, helping to moisturize and soften the skin. However, it is unstable and prone to oxidation, which can lead to skin irritation or clogged pores.

Emollient
BenefitModerate 1.5 / 4
Hydration i2 / 4

Whether the ingredient helps increase the skin’s water content — humectants that attract water, ingredients that reduce water loss, or ones that make skin feel less dry.

Soothing i0.5 / 4

Whether it can calm the skin — linked to less redness, irritation, discomfort, or visible reactivity.

RiskLow 1 / 4
Acne aggravation i1 / 4

Whether it may worsen breakouts — clogging pores, feeling heavy on acne-prone skin, or triggering comedones in some users.

Irritation i1 / 4

Risk of short-term irritation — stinging, burning, dryness, redness, or discomfort. Common for strong actives, acids, retinoids, fragrances, and harsh surfactants.

Rated by SpottyLabs' ingredient methodology, independent of brands.

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Frequently asked questions

What is the difference between squalene and squalane?
Squalene is a natural lipid found in human sebum, but it is unstable and oxidizes quickly. Squalane is a hydrogenated form of squalene, making it stable, non-oxidizing, and more suitable for cosmetic formulations.
Why is squalene less common in skincare than squalane?
Squalene's instability and tendency to oxidize make it less desirable for skincare products compared to its hydrogenated, stable form, squalane. Oxidation can lead to product degradation and potential skin issues.