sh-Polypeptide-11

sh-Polypeptide-11 is a synthetic protein that mimics a human growth factor, specifically Fibroblast Growth Factor-4. It is designed to promote cell proliferation and differentiation. In cosmetic formulations, it is included for its potential to support skin vitality and regeneration.

BenefitGood 2.7 / 4

Anti aging i2.7 / 4

Whether it can help visible signs of aging — fine lines, wrinkles, loss of firmness, or photoaging.

Texture i2.4 / 4

Whether it can improve smoothness and surface texture — roughness, flaking, clogged pores, or unevenness. Exfoliating acids, retinoids, and smoothing moisturizers may score here.

RiskLow 0.5 / 4

Systemic exposure i0.5 / 4

Whether it has meaningful potential to be absorbed into the body at levels that may matter biologically. Most cosmetic ingredients score low unless there is known concern or high exposure.

Rated by SpottyLabs' ingredient methodology, independent of brands.

What it helps with

• Supports cell proliferation
• Promotes skin vitality
• Aids in tissue repair

Things to watch

• Potential for systemic absorption, though generally considered low risk in topical applications.

Products with sh-Polypeptide-11

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Frequently asked questions

What is sh-Polypeptide-11?

sh-Polypeptide-11 is a bio-engineered protein that acts as a synthetic version of human Fibroblast Growth Factor-4 (FGF-4). It is used in skincare to encourage cellular activity.

What are the benefits of sh-Polypeptide-11 for skin?

It is thought to stimulate skin cell growth and renewal, contributing to improved skin texture, firmness, and overall vitality, particularly in anti-aging formulations.