sh-Polypeptide-1

sh-Polypeptide-1 is a synthetic protein that mimics a naturally occurring human growth factor. It is designed to support cell growth and proliferation. In skincare, it is often included for its potential to promote skin regeneration and repair processes.

BenefitGood 2.8 / 4

Anti aging i2.8 / 4

Whether it can help visible signs of aging — fine lines, wrinkles, loss of firmness, or photoaging.

Texture i2.5 / 4

Whether it can improve smoothness and surface texture — roughness, flaking, clogged pores, or unevenness. Exfoliating acids, retinoids, and smoothing moisturizers may score here.

RiskLow 0.5 / 4

Systemic exposure i0.5 / 4

Whether it has meaningful potential to be absorbed into the body at levels that may matter biologically. Most cosmetic ingredients score low unless there is known concern or high exposure.

Rated by SpottyLabs' ingredient methodology, independent of brands.

What it helps with

• Supports skin regeneration
• Promotes cell proliferation
• Aids in skin repair

Things to watch

• Potential for systemic absorption, though generally considered low risk in topical applications.

Products with sh-Polypeptide-1

Browse all products →

Frequently asked questions

What is sh-Polypeptide-1?

sh-Polypeptide-1 is a synthetic version of a human growth factor called Basic Fibroblast Growth Factor (bFGF). It is produced through biotechnology and is used in cosmetics for its potential skin benefits.

How does sh-Polypeptide-1 benefit the skin?

It is believed to stimulate cell growth and division, which can help in skin regeneration, repair, and potentially improve the appearance of aging skin by supporting collagen and elastin production.