Quaternium-33

Quaternium-33 is a synthetic quaternary ammonium compound commonly found in hair care products. It functions as a conditioning agent, helping to detangle hair, reduce static, and improve its overall feel and appearance. It can also provide some film-forming properties.

BenefitModerate 1.7 / 4

Hydration i0.5 / 4

Whether the ingredient helps increase the skin’s water content — humectants that attract water, ingredients that reduce water loss, or ones that make skin feel less dry.

RiskLow 1.2 / 4

Irritation i1 / 4

Risk of short-term irritation — stinging, burning, dryness, redness, or discomfort. Common for strong actives, acids, retinoids, fragrances, and harsh surfactants.

Sensitization i0.8 / 4

Risk of allergic contact dermatitis or immune-based reactions. Fragrance allergens, preservatives, botanicals, and some dyes may score here.

Rated by SpottyLabs' ingredient methodology, independent of brands.

What it helps with

• Conditions hair
• Reduces static
• Aids in detangling

Things to watch

• Potential for skin irritation
• May cause allergic reactions

Products with Quaternium-33

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