Niacin

Niacin, also known as nicotinic acid or vitamin B3, is an essential nutrient involved in many bodily functions. When applied topically, it can help improve skin barrier function and reduce inflammation. Orally, it supports energy metabolism and can help manage cholesterol levels.

BenefitGood 2.8 / 4

Barrier support i2.5 / 4

Whether it supports the skin barrier — restoring lipids, reducing water loss, aiding barrier repair, or strengthening the skin’s protective function.

Soothing i2 / 4

Whether it can calm the skin — linked to less redness, irritation, discomfort, or visible reactivity.

RiskModerate 1.5 / 4

Irritation i1.5 / 4

Risk of short-term irritation — stinging, burning, dryness, redness, or discomfort. Common for strong actives, acids, retinoids, fragrances, and harsh surfactants.

Rated by SpottyLabs' ingredient methodology, independent of brands.

What it helps with

• supports skin barrier
• reduces inflammation
• supports metabolism

Things to watch

• potential for flushing (topical)
• gastrointestinal upset (oral)

Frequently asked questions

What is the difference between Niacin and Niacinamide?

Niacin (nicotinic acid) and Niacinamide (nicotinamide) are both forms of Vitamin B3. While Niacinamide is commonly used in skincare for its anti-inflammatory and barrier-supporting properties with less irritation, Niacin is primarily used orally for its systemic health benefits, though it can cause flushing.