What does Hexapeptide-9 do for the skin?

Hexapeptide-9 is a peptide that helps stimulate the skin's natural collagen production, which can lead to improved skin firmness, elasticity, and a reduction in the appearance of fine lines and wrinkles.

Is Hexapeptide-9 suitable for sensitive skin?

Yes, Hexapeptide-9 is generally considered gentle and well-tolerated, making it suitable for most skin types, including sensitive skin. It is not typically associated with irritation.

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Hexapeptide-9

Hexapeptide-9 is a synthetic peptide composed of six amino acids. It is designed to mimic a fragment of collagen, signaling the skin to produce more of its own collagen. This process helps to improve skin elasticity, reduce the appearance of wrinkles, and support the skin's natural repair mechanisms. It is generally well-tolerated and suitable for most skin types.

PeptideVegan

BenefitGood 2.8 / 4

Anti aging i2.8 / 4

Whether it can help visible signs of aging — fine lines, wrinkles, loss of firmness, or photoaging.

Texture i2 / 4

Whether it can improve smoothness and surface texture — roughness, flaking, clogged pores, or unevenness. Exfoliating acids, retinoids, and smoothing moisturizers may score here.

Barrier support i1.5 / 4

Whether it supports the skin barrier — restoring lipids, reducing water loss, aiding barrier repair, or strengthening the skin’s protective function.

RiskLow 0.5 / 4

Sensitization i0.5 / 4

Risk of allergic contact dermatitis or immune-based reactions. Fragrance allergens, preservatives, botanicals, and some dyes may score here.

Irritation i0.5 / 4

Risk of short-term irritation — stinging, burning, dryness, redness, or discomfort. Common for strong actives, acids, retinoids, fragrances, and harsh surfactants.

Rated by SpottyLabs' ingredient methodology, independent of brands.

What it helps with

Supports collagen production
Reduces appearance of wrinkles
Promotes skin regeneration
Improves skin elasticity

Pairs well with

Vitamin C — Synergistic in supporting collagen synthesis and antioxidant protection.
Retinoid — Complements retinoid action in promoting skin renewal and collagen production, potentially reducing irritation.

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Products with Hexapeptide-9

Caudalie

Resveratrol-Lift Firming Cashmere Cream

4.3/ 515/22/13

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Frequently asked questions

What does Hexapeptide-9 do for the skin?: Hexapeptide-9 is a peptide that helps stimulate the skin's natural collagen production, which can lead to improved skin firmness, elasticity, and a reduction in the appearance of fine lines and wrinkles.
Is Hexapeptide-9 suitable for sensitive skin?: Yes, Hexapeptide-9 is generally considered gentle and well-tolerated, making it suitable for most skin types, including sensitive skin. It is not typically associated with irritation.