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Glutathione

Glutathione is a powerful antioxidant naturally produced in the body, composed of three amino acids: cysteine, glycine, and glutamic acid. In skincare, it helps protect cells from oxidative damage caused by free radicals and environmental stressors. It is also explored for its potential to influence skin pigmentation.

NoneAntioxidantVeganEvidence: Medium
BenefitGood 2.8 / 4
Pigmentation i2.5 / 4

Whether it can help uneven tone, dark spots, melasma-like discoloration, or post-inflammatory hyperpigmentation — including brightening and tyrosinase-inhibiting ingredients.

Soothing i1 / 4

Whether it can calm the skin — linked to less redness, irritation, discomfort, or visible reactivity.

Uv protection i1 / 4

Whether it provides direct protection against UV radiation.

Texture i1 / 4

Whether it can improve smoothness and surface texture — roughness, flaking, clogged pores, or unevenness. Exfoliating acids, retinoids, and smoothing moisturizers may score here.

RiskVery low 0 / 4

Rated by SpottyLabs' ingredient methodology, independent of brands.

What it helps with

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Frequently asked questions

What is glutathione and how does it benefit skin?
Glutathione is a potent antioxidant that helps neutralize free radicals, protecting skin cells from damage. It may also contribute to a brighter complexion by influencing melanin production pathways.
Can glutathione be absorbed topically?
Topical absorption of glutathione is a subject of ongoing research, with some studies suggesting limited penetration. Formulations are often designed to enhance its delivery into the skin.