Glucose Oxidase
Glucose oxidase is an enzyme that catalyzes the oxidation of glucose into hydrogen peroxide and D-glucono-δ-lactone. In cosmetics, it is primarily used for its antimicrobial properties, often as part of a natural preservative system. It works by generating a small amount of hydrogen peroxide, which can inhibit the growth of bacteria and fungi.
NoneEnzymeEvidence: Medium
RiskLow 1 / 4
Irritation i0.8 / 4
Risk of short-term irritation — stinging, burning, dryness, redness, or discomfort. Common for strong actives, acids, retinoids, fragrances, and harsh surfactants.
Sensitization i0.5 / 4
Risk of allergic contact dermatitis or immune-based reactions. Fragrance allergens, preservatives, botanicals, and some dyes may score here.
Rated by SpottyLabs' ingredient methodology, independent of brands.
What it helps with
- Antimicrobial action
- Natural preservative
Things to watch
- Potential for irritation at high concentrations
- May cause sensitization in some individuals
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Frequently asked questions
- What is glucose oxidase?
- Glucose oxidase is an enzyme that helps break down glucose, producing hydrogen peroxide as a byproduct. This hydrogen peroxide acts as a natural antimicrobial agent in cosmetic formulations.
- Is glucose oxidase safe for sensitive skin?
- While generally considered safe, the hydrogen peroxide produced by glucose oxidase can be irritating to very sensitive skin types, especially at higher concentrations. Patch testing is recommended.
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