What is cyanocobalamin?

Cyanocobalamin is a synthetic form of Vitamin B12, an essential nutrient that plays a vital role in metabolism, nerve function, and red blood cell formation.

Can cyanocobalamin be absorbed through the skin?

While some studies suggest limited topical absorption, the primary way to obtain the benefits of Vitamin B12 is through diet or supplementation. Its role in topical skincare is primarily for its potential soothing properties.

Home › Ingredients › Cyanocobalamin

Cyanocobalamin

Cyanocobalamin is a synthetic form of Vitamin B12, an essential nutrient. In skincare, it's sometimes included for its potential to soothe and support skin health, though its topical benefits are not as extensively studied as its dietary role. It is crucial for various bodily functions, including nerve tissue health, brain function, and red blood cell production.

VitaminVegan

BenefitModerate 1.5 / 4

Soothing i1.5 / 4

Whether it can calm the skin — linked to less redness, irritation, discomfort, or visible reactivity.

Barrier support i0.5 / 4

Whether it supports the skin barrier — restoring lipids, reducing water loss, aiding barrier repair, or strengthening the skin’s protective function.

RiskLow 0.5 / 4

Sensitization i0.5 / 4

Risk of allergic contact dermatitis or immune-based reactions. Fragrance allergens, preservatives, botanicals, and some dyes may score here.

Rated by SpottyLabs' ingredient methodology, independent of brands.

What it helps with

soothing skin
supporting skin health

See how this matches your skin

Find out exactly what you put onto your skin. Scan any product before you buy. Free and independent — no brand is paying us. Available on Android and iOS.

QR code linking to the SpottyLabs app on Google Play

QR code linking to the SpottyLabs app on the App Store

Products with Cyanocobalamin

BYOMA

Bio-Collagen Radiance Facial Mask

4.4/ 59/20/3

HOUSE OF DOHWA

Peach Blossom Overnight Mask

4.3/ 57/18/3

TRESemmé

Rich Moisture Shampoo (Vitamin E)

3.7/ 54/14/12

Browse all products →

Frequently asked questions

What is cyanocobalamin?: Cyanocobalamin is a synthetic form of Vitamin B12, an essential nutrient that plays a vital role in metabolism, nerve function, and red blood cell formation.
Can cyanocobalamin be absorbed through the skin?: While some studies suggest limited topical absorption, the primary way to obtain the benefits of Vitamin B12 is through diet or supplementation. Its role in topical skincare is primarily for its potential soothing properties.