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Chlorhexidine Dihydrochloride

Chlorhexidine dihydrochloride is a broad-spectrum antiseptic and disinfectant. It is highly effective against a wide range of bacteria, yeasts, and some viruses. It is commonly used in medical settings for skin disinfection and in oral care for treating gum disease.

NoneAntisepticVeganEvidence: High
BenefitStrong 3.5 / 4
RiskHigh 2.5 / 4
Irritation i1.5 / 4

Risk of short-term irritation — stinging, burning, dryness, redness, or discomfort. Common for strong actives, acids, retinoids, fragrances, and harsh surfactants.

Sensitization i1 / 4

Risk of allergic contact dermatitis or immune-based reactions. Fragrance allergens, preservatives, botanicals, and some dyes may score here.

Systemic exposure i0.5 / 4

Whether it has meaningful potential to be absorbed into the body at levels that may matter biologically. Most cosmetic ingredients score low unless there is known concern or high exposure.

Rated by SpottyLabs' ingredient methodology, independent of brands.

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Frequently asked questions

What is chlorhexidine dihydrochloride used for?
Chlorhexidine dihydrochloride is a powerful antiseptic used in oral rinses to treat gingivitis and reduce plaque, and in medical settings for skin disinfection before procedures.
Are there side effects to using chlorhexidine?
Common side effects include temporary tooth staining, taste alteration, and oral irritation. Serious allergic reactions are rare but require immediate medical attention.