What is 5-Bromo-5-nitro-1,3-dioxane?

5-Bromo-5-nitro-1,3-dioxane is a chemical compound used as a preservative in cosmetic and personal care products to inhibit microbial growth.

Is 5-Bromo-5-nitro-1,3-dioxane safe?

Its safety is debated due to its ability to release formaldehyde, a known allergen and irritant. Regulatory bodies have set limits on its concentration in products.

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5-Bromo-5-nitro-1,3-dioxane

5-Bromo-5-nitro-1,3-dioxane is a formaldehyde-releasing preservative used in cosmetics and personal care products. It helps prevent the growth of bacteria, yeasts, and molds, extending product shelf life. Its use is restricted in some regions due to concerns about formaldehyde release and potential for irritation.

NonePreservativeVeganEvidence: Medium

BenefitNone 0 / 4

RiskHigh 2.5 / 4

Irritation i2.8 / 4

Risk of short-term irritation — stinging, burning, dryness, redness, or discomfort. Common for strong actives, acids, retinoids, fragrances, and harsh surfactants.

Sensitization i2.5 / 4

Risk of allergic contact dermatitis or immune-based reactions. Fragrance allergens, preservatives, botanicals, and some dyes may score here.

Rated by SpottyLabs' ingredient methodology, independent of brands.

Things to watch

May release formaldehyde
Potential skin irritant
Potential sensitizer

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Frequently asked questions

What is 5-Bromo-5-nitro-1,3-dioxane?: 5-Bromo-5-nitro-1,3-dioxane is a chemical compound used as a preservative in cosmetic and personal care products to inhibit microbial growth.
Is 5-Bromo-5-nitro-1,3-dioxane safe?: Its safety is debated due to its ability to release formaldehyde, a known allergen and irritant. Regulatory bodies have set limits on its concentration in products.